Cell BiologybioRxivPreprint
Human Adenovirus (HAdV) mediated inhibition of the tumor suppressor p53 is controlled by SUMOylation of the viral E2A/DBP protein
Miona Stubbe, Hans Christian Stubbe, Julia Mai…·Sabrina Schreiner
This study identifies SUMOylation of HAdV E2A/DBP as a mechanism to inhibit p53 activity and apoptosis, revealing a novel pathway for viral oncogenic potential.
DOI 10.1101/2025.02.07.636424