Author

Fernando López‐Casillas

Universidad Nacional Autónoma de MéxicoORCID 0000-0002-3689-1824Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alexander B. TayloriD· 1 shared Andrew P. HinckiD· 1 shared Caroline S. HilliD· 1 shared Chang‐Hyeock ByeoniD· 1 shared Cynthia S. HinckiD· 1 shared Daniel J. BernardiD· 1 shared Emma K. PunchiD· 1 shared Isabella O. ConwayiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Alexander B. TaylorORCID

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1 paper

Recent·Most cited

Structures of TGF-beta with betaglycan and the signaling receptors reveal the mechanism whereby betaglycan potentiates receptor complex assembly and signaling

Łukasz Wieteska, Alexander B. Taylor, Emma K. Punch, Jonathan A. Coleman, Isabella O. Conway, Yeu‐Farn Lin, Chang‐Hyeock Byeon, Cynthia S. Hinck, Troy C. Krzysiak, Rieko Ishima, Fernando López‐Casillas, Peter Cherepanov, Daniel J. Bernard, Caroline S. Hill, Andrew P. Hinck

This study determines the structure of TGF-beta bound to betaglycan and its signaling receptors, revealing mechanisms of ligand selectivity and signal potentiation.

Nature Communications · Feb 26, 2025Peer-reviewedBiophysics