Peter Cherepanov

SERINC5 Is the Primary Target of Retroviral Antagonists Among Human SERINC Paralogs and Requires a Tri-Cysteine Motif for Its Counteraction by HIV-1 Nef

This paper identifies SERINC5 as the primary target of retroviral antagonists and shows that a tri-cysteine motif in intracellular loop 4 is critical for its downregulation by HIV-1 Nef.

HTLV-1 intasome recruits the PP2A-B56 holoenzyme and restricts its phosphatase activity

The paper shows HTLV-1 integrase recruits PP2A-B56 holoenzyme, structurally inhibiting its phosphatase activity without affecting infection.

Mechanisms for cross-neutralisation of diverse bat sarbecoviruses

This study identifies cross-neutralizing mAbs against diverse bat sarbecoviruses and characterizes their conserved epitopes for vaccine design.

Timed chromatin invasion during mitosis governs prototype foamy virus integration site selection and infectivity

This study shows that PFV Gag protein interacts with mitotic chromatin, and altered binding affects integration site selection and infectivity.

Structures of TGF-beta with betaglycan and the signaling receptors reveal the mechanism whereby betaglycan potentiates receptor complex assembly and signaling

This study determines the structure of TGF-beta bound to betaglycan and its signaling receptors, revealing mechanisms of ligand selectivity and signal potentiation.

Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1

The paper isolates a broadly neutralizing HIV-1 antibody from an untreated HIV-1 patient and shows memory B cells remain functional despite viral infection.