Author

Christopher A. MacRaild

Monash UniversityORCID 0000-0002-3694-3989Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:plant (other)· 2 Assay:proteomics· 2 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Darren J. CreekiD· 3 shared Ghizal SiddiquiiD· 2 shared Aditya V. VashiiD· 1 shared Alan F. CowmaniD· 1 shared Alexander J. McAuleyiD· 1 shared Alyssa E. BarryiD· 1 shared Anupama KumariD· 1 shared Bang M. TraniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

Darren J. CreekORCID

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Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintFeb 25, 2026

MMV687794 blocks Plasmodium falciparum invasion of red blood cells by targeting a Surface-associated Lipid-Interacting Rhoptry Protein, PfSLIRP

Dawson B. Ling, Ghizal Siddiqui, Christopher A. MacRaild…·Paul R. Gilson

This study identifies MMV687794 as an inhibitor of Plasmodium falciparum RBC invasion by targeting PfSLIRP, a rhoptry protein involved in lipid metabolism and vacuole formation.

DOI 10.64898/2026.02.24.707847

plant (other)proteomics

Pharmacology & ToxicologyInternational Journal for Parasitology Drugs and Drug ResistancePeer-reviewedNov 24, 2025

Validation of Solvent Proteome Profiling for Antimalarial Drug Target Deconvolution

Yijia Ji, Joshua P. Morrow, Christopher A. MacRaild…·Ghizal Siddiqui

This study validates solvent proteome profiling (SPP) as a method to identify antimalarial drug targets in Plasmodium falciparum by detecting ligand-induced protein stability changes.

2 citations

plant (other)proteomics

MicrobiologybioRxivPreprintMay 22, 2024

Use of Stem Cell-Derived Cardiomyocyte and Nasal Epithelium Models to Establish a Multi-Tissue Model Platform to Validate Repurposed Drugs Against SARS-CoV-2 Infection

Nathan Gödde, Carmel O’Brien, Elizabeth Vincan…·Seshadri S. Vasan

The paper validates repurposed drugs against SARS-CoV-2 using stem cell-derived cardiomyocyte and nasal epithelium models, confirming fluvoxamine's antiviral efficacy in combination with other drugs.

DOI 10.1101/2024.05.22.595397

humanexperimental assay