Author

Matías Lira

Pontificia Universidad Católica de ChileORCID 0000-0002-3698-4553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Douglas J. LamontiD· 1 shared Felipe A. CourtiD· 1 shared Felipe Véliz‐ValverdeiD· 1 shared Gabriel QuiroziD· 1 shared Gonzalo UretaiD· 1 shared Hernán HuertaiD· 1 shared J César Cárdenas· 1 shared Macarena S. ArrázolaiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Douglas J. LamontORCID

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1 paper

Recent·Most cited

Necroptosis inhibition counteracts neurodegeneration, memory decline and key hallmarks of aging, promoting brain rejuvenation.

Macarena S. Arrázola, Matías Lira, Gabriel Quiroz, Felipe Véliz‐Valverde, Somya Iqbal, Samantha L. Eaton, Rachel Kline, Douglas J. Lamont, Hernán Huerta, Gonzalo Ureta, Sebastián Bernales, J César Cárdenas, Waldo F. Cerpa, Thomas M. Wishart, Felipe A. Court

This study shows that inhibiting necroptosis in aged mice reduces axonal degeneration, neuroinflammation, and memory decline, promoting brain rejuvenation.

Aging Cell · Mar 27, 2023Peer-reviewedNeuroscience