Author

Hernán Huerta

Universidad MayorORCID 0000-0002-7392-3311Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Gabriel QuiroziD· 3 shared César CárdenasiD· 2 shared Christian Enrique González-BillaultiD· 2 shared Adrián G. PalaciosiD· 1 shared Alejandro Acevedo· 1 shared Alenka LovyiD· 1 shared Álvaro O. ArdilesiD· 1 shared Andrea Puebla-Huerta· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Gabriel QuirozORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell Biologynpj AgingPeer-reviewedFeb 21, 2025

Calcium (Ca2+) fluxes at Mitochondria-ER Contact Sites (MERCS) are a new target of senolysis in Therapy-Induced Senescence (TIS).

Andrea Puebla-Huerta, Hernán Huerta, Camila Quezada-Gutiérrez…·César Cárdenas

This study shows that inhibiting ER-mitochondria Ca2+ flux is a new target for senolysis in therapy-induced senescence.

22 citationstop 2%

humanexperimental assay

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NeurosciencebioRxivPreprintSep 7, 2023

Ketogenic diet administration later in life improves memory and regulates the synaptic cortical proteome through the cAMP/PKA signaling pathway in aging mice.

Diego Acuña-Catalán, Samah Shah, Cameron Wehrfritz…·Christian Enrique González-Billault

This study shows that a short-term cyclic ketogenic diet improves memory and synaptic plasticity in aged mice by modulating the cAMP/PKA signaling pathway and cytoskeleton dynamics.

DOI 10.1101/2023.09.07.556691

mouseproteomics

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NeuroscienceAging CellPeer-reviewedMar 27, 2023

Necroptosis inhibition counteracts neurodegeneration, memory decline and key hallmarks of aging, promoting brain rejuvenation.

Macarena S. Arrázola, Matías Lira, Gabriel Quiroz…·Felipe A. Court

This study shows that inhibiting necroptosis in aged mice reduces axonal degeneration, neuroinflammation, and memory decline, promoting brain rejuvenation.

28 citations

mouseexperimental assay

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NeuroscienceThe EMBO JournalPeer-reviewedOct 31, 2022

Control of mammalian brain aging by the unfolded protein response (UPR)

Felipe Cabral‐Miranda, Giovanni Tamburini, Gabriela Martínez…·Claudio A. Hetz

The paper shows that manipulating the UPR pathway can restore brain function and reduce aging-related deficits.

97 citationstop 1%

mouseexperimental assay

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