Oleg A. Kuchur

This paper develops and evaluates a copper-antibody conjugate for targeted chemodynamic therapy of HER2-positive breast cancer, showing effective ROS generation and cytotoxicity.

This study identifies NONO as a redox sensor in MYCN-amplified neuroblastoma cells, showing that its downregulation by oxidative stress synergizes with auranofin to induce cell death.

This study shows that the Atox1-Cyclin D1 loop is critical for survival of TP53-inactivated tumor cells, with its activity dependent on TP53 status.