Author
The University of Texas Southwestern Medical CenterORCID 0000-0002-3711-818XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Ashlesha Gogate, Wei-Chen Chen, Mpathi Nzima…·Maria H. Chahrour
This study uses CRISPRi Perturb-seq to analyze 1,408 autism risk genes in human cortical neurons, identifying 215 genes that cause global transcriptomic dysregulation and uncovering shared transcriptional pathways.
Sushama Sivakumar, Yihan Wang, Sean C. Goetsch…·Nikhil V. Munshi
This study benchmarks and optimizes Perturb-seq in human pluripotent stem cells, identifying shared regulatory networks during cardiomyocyte differentiation.
Arun Sethuraman, Wei-Chen Chen, Margaret Wanjiku, Karin S. Dorman
The paper introduces MULTICLUST, a fast maximum likelihood method for clustering multiallelic genotypes to infer genetic population structure, showing comparable accuracy and efficiency to existing methods.