Luohao Xu

This paper presents a nearly complete haplotype-resolved chicken genome using trio-sequencing and long-read data, identifying gaps and structural variants in dot chromosomes.

HapFold improves haplotype reconstruction for diploid genomes by combining graph-based and sequence-based scaffolding methods, achieving high accuracy and contiguity.

The paper introduces a protocol to integrate spatial transcriptomics and multiplex immunofluorescence in FFPE tissues, enabling multi-omic analysis at single-cell resolution in colorectal cancer samples.

The paper assembles the Y chromosome of Bactrocera dorsalis, identifies amplified genes related to male fertility, and suggests their role in high fecundity.

The paper reports a near-complete genome assembly of a great bustard using frozen wild samples, revealing ancestral karyotype features and low genetic diversity.

The paper shows that pericentromeric heterochromatin (PCH) influences chromosome compartmentalization and contributes to the evolution of homomorphic sex chromosomes in fish.

This study presents a nearly complete duck genome assembly, revealing conserved and convergent chromosome architectures between birds and mammals, including TAD organization and W chromosome evolution.

The paper presents high-quality chromosome-level genomes of two tilapia species, revealing repeat sequence evolution and identifying a candidate female-determining gene.

This study evaluates sequencing technologies and assembly strategies to improve genome completeness in a non-model organism, focusing on resolving dark matter regions like transposable elements and GC-rich areas.

This study creates the first single-cell chromatin accessibility atlas of the lancelet, revealing regulatory elements and developmental trajectories.