Xiangning Ding

This study shows that DNA- and RNA-sensing immune pathways differently control genital HSV-2 infection and prevent neuroinvasion.

This paper uses single-cell proteomics by mass spectrometry (SCP-MS) to analyze mouse kidney cells, revealing previously undetected protein-level heterogeneity, including a proliferative subset of distal convoluted tubule cells.

This study uses single-cell RNA sequencing to analyze the temporal cellular responses in the brain during HSV-1 infection, identifying distinct immune cell subpopulations and their roles in both protective and pathological processes.

The paper compares single-cell transcriptomic data of lung tissues from bats, cats, tigers, and pangolins to analyze viral receptor distribution and immune responses to respiratory viruses.

This paper improves prime editing by modifying the reverse transcriptase component to enhance efficiency and enable delivery via split AAV vectors.

This study creates the first single-cell chromatin accessibility atlas of the lancelet, revealing regulatory elements and developmental trajectories.

This study creates the first single cell atlas of T21 cerebral cortex, identifying dysregulated genes and developing a platform for data exploration.

This study creates the first single-cell brain atlas of domestic pigs, identifies cell types and their spatial distribution, and compares them with other species to reveal evolutionary and disease-related insights.

This study uses single-cell RNA-seq to analyze transcriptome dynamics during human early neural differentiation, identifying novel transcription factors and regulatory elements involved in the process.