Author

Dongsheng Chen

BGI Group (China)ORCID 0000-0003-2005-2353Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Chaochao Cai· 1 shared Deanna M. MarchioniniiD· 1 shared Duo CheniD· 1 shared Erin E. Furr-StimmingiD· 1 shared Fang CheniD· 1 shared Feiyue Wang· 1 shared Gang� LiiD· 1 shared Guang LiiD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperDevelopmental Biology

Chaochao Cai

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 27, 2020

HAP40 is a conserved central regulator of Huntingtin and a specific modulator of mutant Huntingtin toxicity

Shiyu Xu, Gang� Li, Xin Ye…·Sheng Zhang

This study identifies HAP40 as a conserved regulator of Huntingtin, showing it maintains HTT stability and modulates mutant HTT toxicity in both flies and human cells.

2 citations

Drosophilahuman

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Developmental BiologybioRxivPreprintMar 17, 2020

Single cell chromatin accessibility of the developmental cephalochordate

Dongsheng Chen, Zhen J. Huang, Xiangning Ding…·Xun Xu

This study creates the first single-cell chromatin accessibility atlas of the lancelet, revealing regulatory elements and developmental trajectories.

DOI 10.1101/2020.03.17.994954

ATAC-seqexperimental assay

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