Daniel J. Beard

This paper develops shear-activated nanoparticles delivering nitroglycerin to improve ischaemic stroke outcomes by enhancing collateral vessel perfusion.

This study develops a new MRI protocol using 2DG-CESL to measure glucose metabolism in a rat stroke model and shows it provides a biomarker of disturbed metabolism with high effect size.

This study shows rapamycin reduces brain pericyte contraction during ischemia but not viability, improving capillary diameter and openness after stroke.

This study shows that post-recanalization rapamycin treatment improves cerebral blood flow and functional outcomes in rats after ischemic stroke.

This study investigates cerebrovascular changes in the hippocampus after cortical stroke, showing sustained vascular leakage and structural remodeling beyond the primary infarct site.