Developmental BiologybioRxivPreprint
LSD1-mediated enhancer silencing enables endocrine cell development through attenuation of retinoic acid signalling.
Nicholas K. Vinckier, Nisha A. Patel, Allen Wang…·Maike Sander
The paper shows LSD1-mediated enhancer silencing limits RA signaling duration during endocrine cell development by suppressing persistent enhancer activity.
DOI 10.1101/716647