Rotavirus NSP1 activates human NLRP1 inflammasome
Qiru Zeng, Jinyi Sun, Stefano Bonazza, Debajyoti Chakraborty, Alexander Borodavka, Siyuan Ding
This study shows that rotavirus NSP1 activates the NLRP1 inflammasome through proteasomal degradation, independent of double-stranded RNA.
bioRxiv · Oct 27, 2026 · PreprintMicrobiology