Rotavirus NSP1 activates human NLRP1 inflammasome
Qiru Zeng, Jinyi Sun, Stefano Bonazza…·Siyuan Ding
This study shows that rotavirus NSP1 activates the NLRP1 inflammasome through proteasomal degradation, independent of double-stranded RNA.
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Queen's University BelfastORCID 0000-0001-9395-5620Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Qiru Zeng, Jinyi Sun, Stefano Bonazza…·Siyuan Ding
This study shows that rotavirus NSP1 activates the NLRP1 inflammasome through proteasomal degradation, independent of double-stranded RNA.
Stefano Bonazza, Hannah L. Turkington, Swathi Sukumar…·David Courtney
The paper identifies myoferlin as a conserved host factor essential for late-stage vRNP trafficking in enveloped RNA viruses like IAV, RSV, and SeV.
Hannah L Coutts, Swathi Sukumar, Hannah L. Turkington…·David G Courtney
This study identifies RBM3 as a host factor that stabilizes influenza A virus mRNA at cooler temperatures, enhancing viral replication in the upper respiratory tract.