Rotavirus NSP1 activates human NLRP1 inflammasome
Qiru Zeng, Jinyi Sun, Stefano Bonazza…·Siyuan Ding
This study shows that rotavirus NSP1 activates the NLRP1 inflammasome through proteasomal degradation, independent of double-stranded RNA.
Author
Indian Institute of Science BangaloreORCID 0000-0002-1254-6313Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Qiru Zeng, Jinyi Sun, Stefano Bonazza…·Siyuan Ding
This study shows that rotavirus NSP1 activates the NLRP1 inflammasome through proteasomal degradation, independent of double-stranded RNA.
Bartika Ghoshal, Debajyoti Chakraborty, Manish Nag…·Siddharth Jhunjhunwala
This study shows that unmodified mRNA can be effectively delivered to immune cells ex vivo via a non-endosomal route without needing nucleoside modifications.
Arnab Chatterjee, Anupam Roy, Thejas Satheesh…·Somnath Dutta
This study investigates the structural and functional dynamics of Staphylococcus aureus α-hemolysin during membrane interaction, revealing its role in cell necrosis and pore formation.