Rotavirus NSP1 activates human NLRP1 inflammasome
Qiru Zeng, Jinyi Sun, Stefano Bonazza…·Siyuan Ding
This study shows that rotavirus NSP1 activates the NLRP1 inflammasome through proteasomal degradation, independent of double-stranded RNA.
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University of CambridgeORCID 0000-0002-5729-2687Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Qiru Zeng, Jinyi Sun, Stefano Bonazza…·Siyuan Ding
This study shows that rotavirus NSP1 activates the NLRP1 inflammasome through proteasomal degradation, independent of double-stranded RNA.
Daoyuan Qian, Julia Acker, Rob M. Scrutton…·Tuomas P. J. Knowles
This paper introduces a framework for quantitatively analyzing phase diagrams of multicomponent systems, revealing two scaling regimes for phase boundaries.
Julia Acker, Xinyu Wang, Daniel Desirò…·Alexander Borodavka
This study shows that phosphorylation enables distinct nucleation mechanisms for NSP5 condensate formation in rotaviruses, depending on strain-specific LLPS propensity.