Author

Xin Wen Hu

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-3737-2786Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

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Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

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Ajay SharmaiD· 1 shared Amanda R. HaltomiD· 1 shared Ashutosh Singh· 1 shared Javiera B Bravo-AlegriaiD· 1 shared Jyothishmathi SwaminathaniD· 1 shared Keri CallegariiD· 1 shared Lei Ming GuoiD· 1 shared Lin XuiD· 1 shared

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1 shared paperNeuroscience

Ajay SharmaORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintOct 15, 2025

REST elevation-dependent chromatin remodeling and alternative Grk6 transcript synthesis hyperactivates Cxcr4-Sdf1 signaling in cerebellar granule cell progenitors

Keri Callegari, Jyothishmathi Swaminathan, Lei Ming Guo…·Vidya Gopalakrishnan

The paper shows that REST elevation in cerebellar granule cell progenitors increases chromatin accessibility, alters Grk6 transcript expression, and hyperactivates Cxcr4-Sdf1 signaling, leading to increased cell migration.

DOI 10.1101/2025.10.15.682654

mouseChIP-seq

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