Keri Callegari

The paper shows that REST elevation in cerebellar granule cell progenitors increases chromatin accessibility, alters Grk6 transcript expression, and hyperactivates Cxcr4-Sdf1 signaling, leading to increased cell migration.

This study develops and validates a mouse model of sepsis-induced cognitive dysfunction, identifying molecular and functional changes in the cerebral microvasculature and their association with cognitive impairment.

This study identifies transcriptomic changes in mouse ischemic cerebral microvessels and finds shared alterations with human stroke data, highlighting pathways relevant for preclinical research.