Author

Ashutosh Singh

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jyothishmathi SwaminathaniD· 2 shared Lori XuiD· 2 shared Vidya GopalakrishnaniD· 2 shared Ajay SharmaiD· 1 shared Amanda R. HaltomiD· 1 shared Donghang ChengiD· 1 shared Javiera B Bravo-AlegriaiD· 1 shared Keri CallegariiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Jyothishmathi SwaminathanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

REST-AKT-SOX2 axis controls neuronal lineage state and Midkine-mediated communication in SHH-medulloblastoma.

Ashutosh Singh, Lei Guo, Jyothishmathi Swaminathan, Donghang Cheng, Yan Yang, Swarnalatha Manickavinayaham, Lori Xu, Vidya Gopalakrishnan

This study identifies the REST-AKT-SOX2 axis as a key regulator of stem/progenitor identity and Midkine-mediated communication in SHH medulloblastoma, highlighting it as a potential therapeutic target.

bioRxiv · Apr 9, 2026 · PreprintCancer Biology

REST elevation-dependent chromatin remodeling and alternative Grk6 transcript synthesis hyperactivates Cxcr4-Sdf1 signaling in cerebellar granule cell progenitors

Keri Callegari, Jyothishmathi Swaminathan, Lei Ming Guo, Ashutosh Singh, Yanwen Yang, Xue Xiao, Tara Dobson, Amanda R. Haltom, Javiera B Bravo-Alegria, Ajay Sharma, Xin Wen Hu, Lin Xu, Vidya Gopalakrishnan

The paper shows that REST elevation in cerebellar granule cell progenitors increases chromatin accessibility, alters Grk6 transcript expression, and hyperactivates Cxcr4-Sdf1 signaling, leading to increased cell migration.

bioRxiv · Oct 15, 2025 · PreprintNeuroscience

Discovery of Prognostic Biomarkers in Gastric Cancer Through Machine Learning and Bioinformatics Analysis of Gene Expression Data

Rohit Kumar Verma, Prashant Kumar Srivastava, Ashutosh Singh

bioRxiv · Jul 29, 2025 · PreprintBioinformatics