Author

Belinda S. Hall

University of SurreyORCID 0000-0002-3753-1978Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Rachel E. SimmondsiD· 2 shared Gillian ElliottiD· 1 shared Greg J. TowersiD· 1 shared Katja Ebert· 1 shared Kerry L. McPhail· 1 shared Kwabena Owusu-Boateng· 1 shared Lauren Kerfoot· 1 shared Lucy EkeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Rachel E. SimmondsORCID

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2 papers

Recent·Most cited

A mycobacterial Sec61 inhibitor disrupts lysosome function by blocking Vacuolar-ATPase biosynthesis.

Belinda S. Hall, Kwabena Owusu-Boateng, Kerry L. McPhail, Wei Q. Shi, Rachel E. Simmonds

The paper shows that mycolactone disrupts lysosome function by inhibiting Vacuolar-ATPase biosynthesis through Sec61 inhibition, leading to proteostatic stress and impaired phagocytic response to M. ulcerans.

European Journal of Cell Biology · Apr 21, 2026Peer-reviewedCell Biology

Differential time-restricted sensitivity of enveloped viruses to Sec61 translocon blockade

Lucy Eke, Belinda S. Hall, Lucy Thorne, Katja Ebert, Lauren Kerfoot, Greg J. Towers, Rachel E. Simmonds, Gillian Elliott

This study investigates how blocking the Sec61 translocon with mycolactone affects the production of enveloped viruses, finding that some viruses resist this inhibition early in infection.

bioRxiv · Feb 3, 2025 · PreprintMicrobiology