Author

Liyong Zeng

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-3753-620XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

C. Li· 1 shared Emily Zhao· 1 shared Gengyi ZouiD· 1 shared Guang PengiD· 1 shared Guocan WangiD· 1 shared Jaffer A. AjaniiD· 1 shared Ming Zhao· 1 shared Noemi Ira· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

C. Li

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1 paper

Recent·Most cited

ARID1A deficiency unleashes centromeric RNA transcription to drive chromosomal instability and boosts PKMYT1 inhibitor efficacy via RNA sensing

C. Li, Xueqian Cheng, Wiezhen Liu, Gengyi Zou, Thi Hong Minh Nguyen, Emily Zhao, Noemi Ira, Liyong Zeng, Yibo Fan, Shilpa S. Dhar, Guocan Wang, Shumei Song, Ming Zhao, Rugang Zhang, Yuan‐Hung Lo, , Guang Peng

This study shows that ARID1A deficiency increases centromeric RNA transcription, causing chromosomal instability and enhancing the effectiveness of PKMYT1 inhibitors through RNA sensing.

bioRxiv · Apr 13, 2026 · PreprintCancer Biology