Nutrient Microenvironments Reprogram Pigment Epithelium Metabolism and Phenotype
Rayne R. Lim, Emily Zhao, Daniel T. Hass, Yekai Wang, Mark Eminhizer, Davide Ortolan, Sheldon Niernberger, Aspen Tong, Bree R Nelson, Marcos Nazario, Vishya Adipudi, Kapil Bharti, James B. Hurley, Jianhai Du, Jennifer R. Chao
This study examines how different nutrient microenvironments affect RPE cell phenotype, function, and metabolism in iPSC and fetal RPE, identifying key metabolic shifts and phenotypic changes.
bioRxiv · Jul 7, 2026 · PreprintCell Biology