Author
University of LeedsORCID 0000-0002-3754-2028Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Oliver Umney, Alistair Curd, Heather L. Martin, Tarek Lewis, Anna Ah-San Tang, Thembaninkosi G. Gaule, Iain W. Manfield, Harikrushnan Balasubramanian, Satya Khuon, Jesse Aaron, Michelle Peckham
The paper uses iPALM to determine the 3D organisation of three proteins in cardiac muscle Z-discs, revealing differences in their arrangement.
PLoS Computational Biology · Sep 28, 2026Peer-reviewedBiophysics
David E. Casas-Mao, Glenn Carrington, Michelle Peckham
The paper determines the cryo-EM structure of shutdown human non-muscle myosin 2A, revealing ionic interactions and explaining differences in shutdown mechanism compared to β-cardiac myosin.
bioRxiv · Oct 15, 2025 · PreprintBiochemistry
Louise Richardson, Ruth Hughes, Colin A. Johnson, Stuart Egginton, Michelle Peckham
This study investigates MEGF10's role in myoblast fusion and muscle hypertrophy, finding that it inhibits fusion and promotes satellite cell adhesion and survival.
Journal of Muscle Research and Cell Motility · Jan 17, 2025Peer-reviewedCell Biology
Rowan D. Taylor, James A. Poulter, Joseph J. B. Cockburn, John Edward Ladbury, Michelle Peckham, Colin A. Johnson
This study investigates how alternative splicing, specifically nonsense-associated altered splicing (NAS), affects the pathogenesis of CEP290-related ciliopathies by analyzing splicing patterns and ciliogenesis in induced pluripotent stem cells.
medRxiv · Mar 3, 2022 · PreprintGenetic & Genomic Medicine