Thembaninkosi G. Gaule

The paper uses iPALM to determine the 3D organisation of three proteins in cardiac muscle Z-discs, revealing differences in their arrangement.

This paper identifies small molecules targeting the Tenascin C fibrinogen-like globe domain to reduce fibrosis in systemic sclerosis by inhibiting Toll-like receptor 4 signaling.

This paper identifies two RAS-binding Affimer proteins that inhibit RAS function and reveal a novel druggable SII/3 pocket.