Jesse Aaron

The paper identifies extensive membrane contact sites between the mealybug endosymbiont Tremblaya and host mitochondria, suggesting these interactions provide essential membrane and metabolic components.

The paper uses iPALM to determine the 3D organisation of three proteins in cardiac muscle Z-discs, revealing differences in their arrangement.

This study identifies myosin VI as a regulator of DNA double-strand break repair, linking ATM signalling to Ku-associated DNA-end stabilisation and suggesting potential therapeutic targeting.

The paper introduces a machine learning-enabled pipeline for volumetric FLIM imaging in living systems, enabling long-term and high-speed data acquisition and analysis.

This paper presents a device for adapting upright light sheet fluorescence microscopy to image samples at air-liquid interface, demonstrating its use on three biological specimens.

OpticalFlow3D measures amorphous motion in 3D fluorescence microscopy images without requiring segmentation or prior motion definitions.

This study shows that septins form mechanosensitive networks under the nucleus to protect it from mechanical stress.

This study shows Myosin VI regulates estrogen receptor activity and gene expression in breast cancer, with MVI inhibition enhancing hormone therapy effectiveness.

The paper introduces an alternating angle milling technique to reduce streaking artifacts in FIB-SEM imaging, improving structural data quality by minimizing non-uniform material removal.

This paper introduces a method to create photochromic and blinking fluorophores by combining rhodamine and coumarin dyes, enhancing SMLM labeling options.

This paper develops a new electron microscopy method to visualize 3D chromatin folding at ultra-resolution in human cells and finds high heterogeneity in chromatin structures.

The paper uses super-resolution microscopy to visualize a chromatin loop in human cells and validates the results with Hi-C data.