ImmunologybioRxivPreprint
Potassium channels mediate the inhibitory effect of exosomes on anti-tumor immunity in head and neck cancer
Ameet Ajit Chimote, Abdulaziz O. Alshwimi, Simran Venkatraman…·Laura Conforti
This study identifies KCa3.1 channels as a target for enhancing immune responses in HNSCC by showing exosomes suppress CD8 T cell function through Ca2+ signaling disruption.
DOI 10.1101/2025.07.25.666838