Author

Maria A. Lehn

University of CincinnatiORCID 0000-0001-8400-7733Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Leyla EsfandiariiD· 2 shared Maulee ShethiD· 2 shared Somchai ChutipongtanateiD· 2 shared Supasek KongsomrosiD· 2 shared Trisha Michel Wise-DraperiD· 2 shared Vinita TakiariD· 2 shared Abdulaziz O. AlshwimiiD· 1 shared Ameet Ajit ChimoteiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Leyla EsfandiariORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologyLab on a ChipPeer-reviewedJan 1, 2026

Label-free monitoring of therapy response in 3D spheroids using lab-on-a-chip impedance spectroscopy

Gregory P. Macke, Maulee Sheth, Manju Sharma…·Leyla Esfandiari

This study uses lab-on-a-chip impedance spectroscopy to monitor real-time changes in 3D head and neck cancer spheroids after radiotherapy.

3 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 25, 2025

Potassium channels mediate the inhibitory effect of exosomes on anti-tumor immunity in head and neck cancer

Ameet Ajit Chimote, Abdulaziz O. Alshwimi, Simran Venkatraman…·Laura Conforti

This study identifies KCa3.1 channels as a target for enhancing immune responses in HNSCC by showing exosomes suppress CD8 T cell function through Ca2+ signaling disruption.

DOI 10.1101/2025.07.25.666838

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJan 13, 2025

Matrix stiffness modulated release of spheroid-derived extracellular vesicles and discovery of Piezo1 cargo

Maulee Sheth, Manju Sharma, Supasek Kongsomros…·Leyla Esfandiari

This study shows that matrix stiffness modulates EV release and cargo from cancer spheroids, with stiff matrices promoting tumorigenic and metastatic profiles in EVs.

4 citations

humanproteomics

𝕏 PostBluesky