Author

Ian Kline

University of ArizonaORCID 0000-0002-3768-0543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

John G. PurdyiD· 2 shared Rebekah L. MokryiD· 2 shared Yuecheng Xi· 2 shared Felicia D. GoodrumiD· 1 shared Magí PassolsiD· 1 shared Maxwell Wegner· 1 shared Melissa A. Moy· 1 shared Nicholas D Armas· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

John G. PurdyORCID

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2 papers

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedAug 19, 2025

Human cytomegalovirus promotes de novo PC synthesis during early virus replication

Ian Kline, Rebekah L. Mokry, Yuecheng Xi…·John G. Purdy

This study shows HCMV increases phosphatidylcholine (PC) levels through de novo synthesis during early replication, independent of late gene expression.

3 citations

humanmetabolomics

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MicrobiologybioRxivPreprintMar 31, 2025

Human Cytomegalovirus Infection Reduces an Endogenous Antiviral Fatty Acid by Promoting Host Metabolism

Yuecheng Xi, Rebekah L. Mokry, Nicholas D Armas…·John G. Purdy

This study shows HCMV infection reduces erucic acid levels, an antiviral fatty acid, by promoting metabolism that increases other fatty acids, thereby evading its antiviral effect.

DOI 10.1101/2025.03.31.646481

humanmetabolomics

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