Author

Yifan Zhou

University of ChicagoORCID 0000-0002-3768-9353Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yifan Zhou3 papers · Dascena (United States)

Biology Disciplines

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Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Xin HeiD· 3 shared Alan R. SandersiD· 2 shared Alena KozlovaiD· 2 shared Hanwen ZhangiD· 2 shared Jubao DuaniD· 2 shared Mengjie CheniD· 2 shared Siwei ZhangiD· 2 shared Zhiping P. PangiD· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenetics

Xin HeORCID

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3 papers

Recent·Most cited

A novel Bayesian factor analysis method improves detection of genes and biological processes affected by perturbations in single-cell CRISPR screening

Yifan Zhou, Kaixuan Luo, Mengjie Chen, Xin He

bioRxiv · Feb 13, 2022 · PreprintGenomics

Multiple genes in cis mediate the effects of a single chromatin accessibility variant on aberrant synaptic development and function in human neurons

Siwei Zhang, Hanwen Zhang, Marc P. Forrest, Yifan Zhou, Vikram A. Bagchi, Alena Kozlova, Marc Dos Santos, Nicolas H. Piguel, Leonardo E. Dionisio, Alan R. Sanders, Zhiping P. Pang, Xin He, Peter Penzes, Jubao Duan

The paper identifies multiple genes in cis regulated by a chromatin accessibility variant that contribute to synaptic dysfunction in human neurons associated with schizophrenia.

bioRxiv · Dec 11, 2021 · PreprintGenetics

Allele-specific open chromatin in human iPSC neurons elucidates functional non-coding disease variants

Siwei Zhang, Hanwen Zhang, Min Qiao, Yifan Zhou, Siming Zhao, Alena Kozlova, Jianxin Shi, Alan R. Sanders, Gao T. Wang, Subhajit Sengupta, Siobhan West, Michael Streit, Chad A. Cowan, Mengjie Chen, Zhiping P. Pang, , Jubao Duan

The paper identifies allele-specific open chromatin (ASoC) variants in human iPSC-derived neurons and shows their strong enrichment in brain disorder risk variants.

bioRxiv · Nov 1, 2019 · PreprintGenetics