Author
Northwestern UniversityORCID 0000-0003-0504-6940Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Miguel Lobete, Leonardo E. Dionisio, Emmarose McCoig…·María Dolores Martin‐de‐Saavedra
This study shows that ASD-associated CNTNAP2 variants reduce sCNTNAP2 levels and impair dendritic arborization through disrupted ectodomain shedding.
Nan Wang, Shasha Zhang, Peter Langfelder…·X. William Yang
This study identifies Msh3 and Pms1 as genetic drivers of CAG-repeat migration in HD mice, leading to selective striatal and cortical pathogenesis.
Nicolas H. Piguel, Shaun S. Sanders, Francesca Isabella De Simone…·Peter Penzes
This study shows that palmitoylation of AnkG-190 stabilizes its localization in dendritic spines, and lithium reduces this modification, affecting its function and interaction with PSD-95.
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel…·Peter Penzes
This study identifies PRRT2 as a key hub in an epilepsy network disrupted by 16p11.2 duplication and shows its correction rescues multiple neuropsychiatric and seizure-related phenotypes in mice.
Siwei Zhang, Hanwen Zhang, Marc P. Forrest…·Jubao Duan
The paper identifies multiple genes in cis regulated by a chromatin accessibility variant that contribute to synaptic dysfunction in human neurons associated with schizophrenia.