Author

Ewa B. Snaar-Jagalska

Leiden UniversityORCID 0000-0002-3772-047XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:organoid / primary culture· 1

Frequent Co-Authors

Gangyin ZhaoiD· 2 shared Arwin GroenewoudiD· 1 shared Gabriel Forn‐CuníiD· 1 shared George Niklaus ThalmanniD· 1 shared Jelle de Vries· 1 shared Jie YiniD· 1 shared Lanpeng CheniD· 1 shared Lanpeng Chen· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Gangyin ZhaoORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer LettersPeer-reviewedFeb 7, 2024

Simultaneous targeting of AMPK and mTOR is a novel therapeutic strategy against prostate cancer

Gangyin Zhao, Gabriel Forn‐Cuní, Marvin Scheers…·Ewa B. Snaar-Jagalska

This study shows that targeting both AMPK and mTOR can inhibit prostate cancer metastasis by blocking the metabolic switch required for tumor growth in new environments.

24 citations

humanexperimental assay

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Cancer BiologybioRxivPreprintAug 28, 2023

Mechano-signaling of prostate tumor initiating cells facilitates their tropism to stiff metastatic niche

Lanpeng Chen, Gangyin Zhao, Marta De Menna…·Ewa B. Snaar-Jagalska

The paper shows that mechanotransduction via TAZ and cytoskeletal tension promotes prostate cancer stem cell metastasis and identifies a YAP/TAZ inhibitor as a potential therapeutic target.

DOI 10.1101/2023.08.28.553410

humanorganoid / primary culture

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