Jasvinder S. Ahuja

Temporal and Functional Relationship between Synaptonemal Complex Morphogenesis and Recombination during Meiosis

The paper investigates the temporal and functional relationship between synaptonemal complex (SC) morphogenesis and recombination during meiosis in budding yeast, showing SC's role in regulating recombination transitions.

Rad51-mediated interhomolog recombination during budding yeast meiosis is promoted by the meiotic recombination checkpoint and the conserved Pif1 helicase

This paper shows that Rad51-mediated interhomolog recombination in budding yeast meiosis is inhibited during Phase 1 to prevent competition with Dmc1, and is promoted by the checkpoint and Pif1 helicase.

Repeated strand invasion and extensive branch migration are hallmarks of meiotic recombination

The paper shows that both noncrossover and crossover meiotic recombination involve synthesis-dependent strand annealing, challenging existing models of recombination mechanisms.

S. cerevisiae Srs2 helicase ensures normal recombination intermediate metabolism during meiosis and prevents accumulation of Rad51 aggregates

This study shows that Srs2 helicase is essential for normal meiotic progression and prevents Rad51 aggregate formation, which could disrupt chromosome segregation.