Nancy M. Hollingsworth

The paper identifies a distinct mode of meiotic chromosome synapsis that occurs independently of homology and is regulated by ATR/Mec1 and Zip1 phosphorylation.

This study identifies the roles of PIF1, RAD54, and RDH54/TID1 in Phase 2 meiotic recombination in budding yeast, showing RDH54/TID1 partially compensates for RAD54 while PIF1 acts independently.

This paper shows that SEN1 has three distinct roles in yeast meiosis: enabling IME1 gene expression, preventing DNA:RNA hybrid accumulation, and facilitating double strand break repair and chromosome synapsis.

This paper identifies a non-canonical interaction between the FHA domain of the yeast kinase Mek1 and RPXKR motifs in its substrates Ndt80 and Rrm3, validated through AlphaFold modeling and genetic analysis.

This paper shows that Rad51-mediated interhomolog recombination in budding yeast meiosis is inhibited during Phase 1 to prevent competition with Dmc1, and is promoted by the checkpoint and Pif1 helicase.

The paper identifies privileged end-adjacent regions near telomeres that maintain DSBs and contribute to higher recombination rates on short chromosomes in yeast.

This study shows that MutSγ activation during meiosis depends on Cdc7-mediated phosphorylation of Msh4, stabilizing the complex and enabling crossover formation.

The paper identifies Mek1 as the kinase responsible for H3 T11 phosphorylation in meiosis and shows H3 T11ph serves as a marker of Mek1 activity.