Author

Jamal El Saghir

University of MichiganORCID 0000-0002-3779-4583Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Akihiro MinakawaiD· 1 shared Anja M. BillingiD· 1 shared Bradley GodfreyiD· 1 shared Céline C. BerthieriD· 1 shared Chenchen HeiD· 1 shared Damian FerminiD· 1 shared Fadhl AlakwaaiD· 1 shared Fatih DemiriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Akihiro MinakawaORCID

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1 paper

Recent·Most cited

Dapagliflozin mitigates hypoxia-induced metabolic stress, kidney tubular cell death and fibrosis

Akihiro Minakawa, Jamal El Saghir, Céline C. Berthier, Moritz Lassé, Soumya Maity, Judy J. Baek, Damian Fermin, Anja M. Billing, Chenchen He, Felix H. Eichinger, John Hartman, Viji Nair, Matthew Fischer, Virginia Vega-Warner, Fadhl Alakwaa, , Jennifer L. Harder

This study shows dapagliflozin reduces hypoxia-induced metabolic stress, cell death, and fibrosis in kidney organoids derived from human pluripotent stem cells.

bioRxiv · Jan 14, 2026 · PreprintCell Biology