Identification of the three zinc-binding sites on Tau protein
Romain La Rocca, Philipp O. Tsvetkov, Andrey V. Golovin, Diane Allegro, Pascale Barbier, Soazig Malesinski, Françoise Guerlesquin, François Devred
This study identifies three zinc-binding sites on the Tau protein using NMR and molecular simulations, providing insights into zinc-induced aggregation mechanisms and potential therapeutic targets.
bioRxiv · Apr 23, 2021Molecular Biology