Author

Euan Joly-Smith

University Medical Center UtrechtORCID 0000-0002-3792-2231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander van OudenaardeniD· 1 shared Amanda Andersson-RolfiD· 1 shared Andreas HilfingeriD· 1 shared Eugenio MarinelliiD· 1 shared Fotini PapazotosiD· 1 shared Hans C. CleversiD· 1 shared Harmjan R. VosiD· 1 shared Kseniia SarievaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Alexander van OudenaardenORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 31, 2026

Single-Cell Inference of Structural States Of Ribosomes

Euan Joly-Smith, Michael A. VanInsberghe, Kseniia Sarieva…·Alexander van Oudenaarden

SCISSOR infers global translation activity in single cells using ribosomal RNA protection signatures, revealing cell cycle and differentiation-related translation variations in human and murine cells.

DOI 10.64898/2026.08.29.747780

humanmouse

Systems BiologyeLifePeer-reviewedDec 16, 2025

Exploiting fluctuations in gene expression to detect causal interactions between genes

Euan Joly-Smith, Mir Mikdad Talpur, Paige Allard…·Andreas Hilfinger

This paper introduces a method to detect causal gene interactions using natural expression fluctuations in genetically identical cells, validated in E. coli synthetic circuits.

DOI 10.7554/elife.92497

E. colibulk RNA-seq