Author

Amanda Andersson-Rolf

Karolinska InstitutetORCID 0000-0002-4262-5370Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Amanda Andersson-Rolf1 paper

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Hans C. CleversiD· 2 shared Alexander van OudenaardeniD· 1 shared Aliaksandra RadzisheuskayaiD· 1 shared Bon‐Kyoung KooiD· 1 shared Cayetano Pleguezuelos‐ManzanoiD· 1 shared Euan Joly-SmithiD· 1 shared Eugenio MarinelliiD· 1 shared Eyleen de Poel· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMolecular Biology

Hans C. CleversORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Single-Cell Inference of Structural States Of Ribosomes

Euan Joly-Smith, Michael A. VanInsberghe, Kseniia Sarieva, Eugenio Marinelli, Robert M. van Es, Paula Sobrevals Alcaraz, Harmjan R. Vos, Amanda Andersson-Rolf, Hans C. Clevers, Alexander van Oudenaarden

SCISSOR infers global translation activity in single cells using ribosomal RNA protection signatures, revealing cell cycle and differentiation-related translation variations in human and murine cells.

bioRxiv · Aug 31, 2026 · PreprintMolecular Biology

Evaluating CRISPR-based Prime Editing for cancer modeling and CFTR repair in intestinal organoids

Maarten H. Geurts, Eyleen de Poel, Cayetano Pleguezuelos‐Manzano, Rurika Oka, Léo Carrillo, Amanda Andersson-Rolf, Matteo Boretto, Jesse E. Brunsveld, Ruben van Boxtel, Jeffrey Matthijn Beekman, Hans C. Clevers

This study evaluates prime editing for modeling cancer mutations and repairing CFTR in intestinal organoids, showing its potential but also highlighting challenges in efficiency and off-target effects.

Life Science Alliance · Aug 9, 2021Peer-reviewedGenetics

Sox2 modulation increases naive pluripotency plasticity

Kathryn Tremble, Giuliano Giuseppe Stirparo, Lawrence E. Bates, Katsiaryna Maskalenka, Hannah T. Stuart, Kenneth Jones, Amanda Andersson-Rolf, Aliaksandra Radzisheuskaya, Bon‐Kyoung Koo, Paul Bertone, José Silva

This study shows that low Sox2 expression in naive pluripotent stem cells enhances their developmental plasticity without impairing neuroectoderm differentiation.

iScience · Feb 7, 2021Peer-reviewedDevelopmental Biology