Author
Royal Netherlands Academy of Arts and SciencesORCID 0000-0001-8418-4393Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Luuk A. Broeils, Jill Pilet, Maria K. Koshkina…·Sebastiaan van Heesch
The paper shows EWSR1::FLI1 fusion drives the production of cancer-specific neoproteins in Ewing sarcoma, revealing a reversible dark proteome with therapeutic potential.
Euan Joly-Smith, Michael A. VanInsberghe, Kseniia Sarieva…·Alexander van Oudenaarden
SCISSOR infers global translation activity in single cells using ribosomal RNA protection signatures, revealing cell cycle and differentiation-related translation variations in human and murine cells.
Rinskje B. Tjeerdsma, Timothy F. Ng, Maurits Roorda…·Marcel A.T.M. van Vugt
This study shows WEE1 inhibitors trigger the integrated stress response via GCN2 activation, leading to translational shutdown, which can be mitigated by low-dose or combination treatments.
Ofri Rabany, Sivan Ben Dror, Maram Arafat…·Daphna Nachmani
The paper identifies rRNA methylation dynamics as a mechanism regulating translation efficiency and HSC fitness during hematopoietic differentiation.
Jan Dreyer, Giulia Ricci, Jeroen van den Berg…·Francesca Mattiroli
This study investigates the acute effects of CAF-1 loss on chromatin assembly during S-phase, revealing multi-level responses including replication slowdown and histone modification changes.