Kseniia Sarieva

Single-Cell Inference of Structural States Of Ribosomes

SCISSOR infers global translation activity in single cells using ribosomal RNA protection signatures, revealing cell cycle and differentiation-related translation variations in human and murine cells.

Multiomics analysis identifies VPA-induced changes in neural progenitor cells, ventricular-like regions, and cellular microenvironment in dorsal forebrain organoids

This study examines VPA-induced changes in dorsal forebrain organoids using multiomics approaches, revealing disruptions in ECM and microenvironment signaling.

Comparing the impact of sample multiplexing approaches for single-cell RNA-sequencing on downstream analysis using cerebellar organoids

This study compares two single-cell RNA-sequencing multiplexing techniques, 10x and Parse, on cerebellar organoids, finding similar cellular diversity but differences in transcript capture and cell stress.

Human organoid model of PCH2a recapitulates brain region-specific pathology

This study develops human organoid models of PCH2a to investigate brain region-specific pathology, finding size reductions in cerebellar organoids and altered proliferation kinetics.

Super-resolution STED imaging in the inner and outer whole-mount mouse retina

This paper establishes a STED microscopy protocol for super-resolution imaging of whole-mount mouse retinas, achieving sub-120 nm resolution for subcellular structures.

Human brain organoid model of maternal immune activation identifies radial glia cells as selectively vulnerable

This study uses a human 3D organoid model to show that maternal immune activation increases radial glia cell vulnerability and identifies species-specific gene responses linked to ASD risk.