Rahuljeet Singh Chadha

The paper introduces MetaboRamics, a method for 16-color metabolic imaging in live cells using stimulated Raman scattering, revealing metabolic changes in EMT and under various stress conditions.

This study maps endothelial-macrophage interactions in diabetic vasculature using single-cell and spatial transcriptomics, identifying TREM2 as a key driver of vascular inflammation and ischemic response in diabetes.

This paper introduces MATRIX-SRS, a method to image TCA cycle activity in live cells, revealing metabolic changes during epithelial-to-mesenchymal transition.

This study uses SRS microscopy to show that endothelial cells store glycogen under diabetes-like stress, which helps them survive glucose starvation and may offer new therapeutic targets for diabetes-related endothelial dysfunction.

This study shows that inhibiting endothelial AGO1 reduces vascular inflammation and atherosclerosis by blocking its non-canonical nuclear role in promoting NF-κB-driven inflammation.