Adrian Colazo

Deep Learning-Augmented Stimulated Raman Imaging for Cell-Type-Specific Metabolic Profiling in Live Neuronal Co-Cultures

This paper develops a deep learning-augmented SRS imaging method to profile metabolism in live neuronal co-cultures, revealing cell-type-specific metabolic responses to various conditions.

MetaboRamics: Highly multiplexed metabolic imaging by stimulated Raman for spatial metabolomics in live cells

The paper introduces MetaboRamics, a method for 16-color metabolic imaging in live cells using stimulated Raman scattering, revealing metabolic changes in EMT and under various stress conditions.

Optical metabolic imaging of the tricarboxylic acid cycle

This paper introduces MATRIX-SRS, a method to image TCA cycle activity in live cells, revealing metabolic changes during epithelial-to-mesenchymal transition.

Single-Cell Metabolic Imaging Reveals Glycogen Driven-Adaptations in Endothelial Cells

This study uses SRS microscopy to show that endothelial cells store glycogen under diabetes-like stress, which helps them survive glucose starvation and may offer new therapeutic targets for diabetes-related endothelial dysfunction.