Vivek Jani

This study shows GSNOR deletion protects male cardiac function with age but may worsen female cardiac function by removing an age-related SNO imbalance.

This study shows that DSG2 deficiency causes cardiac dysfunction by impairing Z-disc and intercalated disc mechanotransduction, leading to structural and functional cardiac defects.

The paper identifies unique proteomic changes in ATTR-CM hearts, showing upregulated endocytosis and downregulated sarcomere proteins compared to controls.