Corrine R. Kliment

This study shows that loss of TFAM in alveolar type 2 cells leads to mitochondrial dysfunction and fibrosis by promoting senescence and a profibrotic secretory program.

This study shows that ANT2 deficiency in AT2 cells promotes ferroptosis and emphysema by impairing bioenergetics and self-renewal.

This study identifies QKI as a regulator of mitochondrial integrity in COPD, showing its protective role against emphysema through maintenance of mitochondrial function.

The paper identifies smoking-associated miRNA regulatory networks in blood and tissue, revealing NDUFA12 as a key target linked to mitochondrial dysfunction in smokers.