Author

Nayra Cárdenes

University of PittsburghORCID 0000-0003-4174-6610Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Delphine BeaulieuiD· 2 shared John SembratiD· 2 shared M. Camila Melo-NarváeziD· 2 shared Mareike LehmanniD· 2 shared Mélanie KönigshoffiD· 2 shared Oliver EickelbergiD· 2 shared Qianjiang HuiD· 2 shared Aditi U. GurkariD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPathology

Delphine BeaulieuORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintJul 18, 2026

Alveolar Epithelial Cell Loss of the Mitochondrial Regulator TFAM Drives Progressive Lung Fibrosis

Qianjiang Hu, Ugochi Onwuka, Nayra Cárdenes…·Mélanie Königshoff

This study shows that loss of TFAM in alveolar type 2 cells leads to mitochondrial dysfunction and fibrosis by promoting senescence and a profibrotic secretory program.

DOI 10.64898/2026.05.28.728065

humanmouse

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GenomicsbioRxivPreprintDec 21, 2024

SenSet, a novel human lung senescence cell gene signature, identifies cell-specific senescence mechanisms

Euxhen Hasanaj, Delphine Beaulieu, Cankun Wang…·Mélanie Königshoff

The paper develops SenSet, a gene signature for human lung senescence, validated in 3D culture models and identifies cell-type specific senescence mechanisms in aging and disease.

7 citations

humanscRNA-seq

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