The developmental basis for scaling of mammalian tooth size
Mona M. Christensen, Outi K. Hallikas, Rishi Das Roy, Vilma Väänänen, Otto E. Stenberg, Teemu J. Häkkinen, Jean‐Christophe François, Robert J. Asher, Ophir D. Klein, Martin Holzenberger, Jukka Jernvall
The paper investigates how mammalian molar teeth scale during development and evolution, finding that the IGF pathway regulates both growth and cusp patterning to achieve size differences.
Proceedings of the National Academy of Sciences · Jun 12, 2023Peer-reviewedDevelopmental Biology