Author

Fernando Martínez López

Karolinska InstitutetORCID 0000-0002-3836-9239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Akira HasegawaiD· 3 shared Chi Wai YipiD· 3 shared Jen-Chien ChangiD· 3 shared Michihira TagamiiD· 3 shared Tsukasa Kouno· 3 shared Yasushi OkazakiiD· 3 shared Youtaro Shibayama· 3 shared Andreas PetriiD· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Akira HasegawaORCID

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3 papers

Recent·Most cited

A single-cell atlas of transcribed cis-regulatory elements in the human genome

Jonathan Moody, Tsukasa Kouno, Miki Kojima, Ikuko Koya, Julio Leon, Akari Suzuki, Akira Hasegawa, Taishin Akiyama, Nobuko Akiyama, Masayuki Amagai, Jen-Chien Chang, Ayano Fukushima‐Nomura, Mika Handa, Kazunori Hino, Mizuki Hino, , Chung-Chau Hon

The paper constructs a single-cell atlas of transcribed cis-regulatory elements in the human genome, revealing gene regulation patterns and trait-gene relationships across cell populations.

bioRxiv · Nov 13, 2023 · PreprintGenomics

Antisense oligonucleotide-mediated perturbation of long non-coding RNA reveals functional features in stem cells and across cell types

Chi Wai Yip, Chung-Chau Hon, Kayoko Yasuzawa, Divya Mundackal Sivaraman, Jordan A. Ramilowski, Youtaro Shibayama, Saumya Agrawal, Anika Vinayak Prabhu, Callum Parr, Jessica Severin, Yan Jun Lan, Josée Dostie, Andreas Petri, Hiromi Nishiyori-Sueki, Michihira Tagami, , Jay W. Shin

The paper performs knockdown of 200 lncRNAs in human iPS cells, identifies 36 with growth inhibition, and finds molecular phenotypes in 29.3% of cases, with higher agreement in molecular than cell growth phenotypes across cell types.

Cell Reports · Dec 1, 2022Peer-reviewedGenomics

Functional Annotation of Human Long Non-Coding RNAs via Molecular Phenotyping

Jordan A. Ramilowski, Chi Wai Yip, Saumya Agrawal, Jen-Chien Chang, Yari Ciani, Ivan V. Kulakovskiy, Mickaël Mendez, Jasmine Li Ching Ooi, John F. Ouyang, Nick Parkinson, Andreas Petri, Leonie Roos, Jessica Severin, Kayoko Yasuzawa, Imad Abugessaisa, , Chinatsu Yamamoto

The paper functionally annotates human long non-coding RNAs by systematically knocking down 285 lncRNAs and analyzing molecular phenotypes using CAGE sequencing.

Genome Research · Jul 1, 2020Peer-reviewedGenomics