Author

Ikuko Koya

RIKEN Center for Integrative Medical SciencesORCID 0000-0002-9522-9873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:experimental assay· 1

Frequent Co-Authors

Hideyuki OkanoiD· 2 shared Jay W. ShiniD· 2 shared Jonathan MoodyiD· 2 shared Julio LeoniD· 2 shared Ken‐ichiro KuboiD· 2 shared Masaki TakaoiD· 2 shared Piero CarninciiD· 2 shared Satoru MorimotoiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Hideyuki OkanoORCID

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2 papers

Recent·Most cited

DAP12-deficient microglia adopt a TREM2-independent antigen-presenting state with a glial-to-neuronal cascade in Nasu-Hakola disease

Julio Leon, Satoshi Yoshinaga, Ikuko Koya, Grecia Palafox, Yoshinari Ando, Ken‐ichiro Kubo, Jonathan Moody, Masaki Takao, Piero Carninci, Jay W. Shin, Carlo Condello, Hideyuki Okano, Chung Chau Hon, Satoru Morimoto

The paper profiles NHD microglia and shows they adopt an antigen-presenting state without TREM2 dependence, triggering glial-to-neuronal changes.

bioRxiv · Oct 11, 2026 · PreprintNeuroscience

A single-cell atlas of transcribed cis-regulatory elements in the human genome

Jonathan Moody, Tsukasa Kouno, Miki Kojima, Ikuko Koya, Julio Leon, Akari Suzuki, Akira Hasegawa, Taishin Akiyama, Nobuko Akiyama, Masayuki Amagai, Jen-Chien Chang, Ayano Fukushima‐Nomura, Mika Handa, Kazunori Hino, Mizuki Hino, , Chung-Chau Hon

The paper constructs a single-cell atlas of transcribed cis-regulatory elements in the human genome, revealing gene regulation patterns and trait-gene relationships across cell populations.

bioRxiv · Nov 13, 2023 · PreprintGenomics