Abbi R. Hernandez

Time restricted feeding with or without ketosis influences metabolism-related gene expression in a tissue-specific manner in aged rats

This study examines how different diets affect metabolism-related gene expression in aged rats' tissues and links these changes to cognitive performance.

A long-term ketogenic diet in young and aged rats has dissociable effects on prelimbic cortex and CA3 ensemble activity

This study examines the effects of a ketogenic diet on neural activity in the prelimbic cortex and CA3 of young and aged rats, finding increased activation in the PL but no change in CA3.

Impairments in fear extinction memory and basolateral amygdala plasticity in the TgF344-AD rat model of Alzheimer's disease are distinct from non-pathological aging.

This study investigates fear extinction memory and basolateral amygdala (BLA) synaptic dysfunction in TgF344-AD rats, finding distinct impairments in AD compared to non-pathological aging.

Age-related alterations in prelimbic cortical neuron Arc expression vary by behavioral state and cortical layer

The paper examines age-related changes in Arc expression in prelimbic cortical neurons during behavior, finding reduced expression linked to multitasking deficits, with no projection neuron specificity in the prelimbic cortex unlike the perirhinal cortex.

Time-restricted feeding from adulthood to old age improves biconditional associative learning in geriatric rats regardless of macronutrient composition

This study shows that time-restricted feeding improves biconditional associative learning in aged rats, regardless of diet type, suggesting potential benefits for cognitive health.

Sex Differences in Age-related Impairments Vary across Cognitive and Physical Assessments in Rats

This study examines sex and age differences in cognitive and physical performance in rats, finding age-related declines in both sexes but no significant sex differences in cognitive tasks.

Age and ketogenic diet have dissociable effects on synapse-related gene expression between hippocampal subregions

This study examines how aging and a ketogenic diet affect synapse-related gene expression in different hippocampal subregions, showing subregion-specific changes.

The Anti-Epileptic Ketogenic Diet Alters Hippocampal Transporter Levels and Reduces Adiposity in Aged Rats

This study shows that a ketogenic diet reduces adiposity and reverses age-related declines in hippocampal transporter expression in aged rats.