Sarah Canetta

This study shows that early developmental fluoxetine exposure impairs adult motivation in mice, which can be reversed by nucleus accumbens mu opioid receptor antagonism.

This study inhibits thalamo-prefrontal projections in adolescent mice and finds altered synaptic connectivity and cognitive deficits in adulthood.

The paper shows that inhibiting parvalbumin interneurons in the prefrontal cortex during juvenile and adolescent periods causes lasting impairments in adult circuit function and behavior, which can be reversed by reactivating these neurons in adulthood.

This study shows that tianeptine, but not fluoxetine, reduces avoidant behavior in mice prenatally exposed to fluoxetine, suggesting it may be a better treatment for altered serotonergic systems.